STUDI IN VIVO : EFEKTIVITAS KOMBUCHA BUNGA KENANGA ( Cananga odorata) DAN EKSTRAK KULIT APEL MANALAGI (Malus sylvestris) SEBAGAI MINUMAN PROBIOTIK ANTI HIPER-URISEMIA

One of the diseases in Indonesia that often occurs in the elderly is gout. Gout treatment is often carried out using drugs such as allopurinol, which will cause side effects so people are advised to choose prevention by cultivating herbal plants. The probiotic drink kombucha from ylang-ylang flowers and apple peel extract can prevent hyperuricemia. This study used a simple randomized block design with a comparison of factors between ylang-ylang flower tea and peel extract. Ylang- ylang flower kombucha was tested, namely alcohol test, antioxidant test, pH test, color intensity, sensory, and uric acid level test in mice. Based on research data, it is known that ylang-ylang flower kombucha and Manalagi apple peel extract have an average alcohol content of 0.5%. The highest antioxidant activity was in F4 with levels of 87.11, and a strong IC50 of 66.29 ppm. The best reduction in uric acid levels was in treatment F4, with a reduction in levels of 05 mg/dL. pH levels have an average of 3.03-3.56. The most liked kombucha’s formula by the panelists was formulation of 60% ylang ylang flower tea and 40% apple peel extract with a brightness level (L) of 23.90, a redness level (a) of 1.76, and a hardening level (b) of 2.70. aroma score 2.2 (not strong), taste 3.3 (quite sour) and liking 3.4 (quite like it)