STUDI PENGGUNAAN OBAT ACE INHIBITOR PADA PASIEN GAGAL JANTUNG DI RSUD R.T NOTOPURO SIDOARJO

Background: Heart failure is caused by the heart failing to pump blood to supply the body's metabolic needs. Heart failure is a clinical syndrome indicated by typical symptoms such as shortness of breath, leg swelling, and fatigue. It is potentially accompanied by signs of increased jugular venous pressure, pneumonia, and peripheral edema. Treatment of heart failure patients with ACE Inhibitors aims to
reduce myocardial remodeling, to prevent vasoconstriction and reduce structural changes in the heart. ACE Inhibitor therapy is beneficial in improving renal blood flow and reducing vascular resistance.
Objective: To determine the pattern of ACE Inhibitor use in heart failure patients which includes dose, type, frequency, route, and duration of administration.
Method: This study was conducted observational and descriptive, with
retrospective and descriptive data collection.
Results and Conclusion: Single use pattern 5 patients (15%), 2 combinations 16 patients (57%) and 3 combinations 12 patients (43%). The most common single use pattern was ramipril (1x2.5mg)po 3 patients (60%), the most common 2 combinations were Ramipril (1x2,5mg)po + Bisoprolol (1x2,5mg)po 5 patients (32%) and Ramipril (1x2,5mg)po + Spironolactone (1x25mg)po 5 patterns (32%), the most common 3 combinations were Ramipril (1x2,5mg)po + Bisoprolol
(1x2,5mg)po + Spironolactone (1x25mg)po 5 patients (32%) and there were 6 switch patterns.