AKTIVITAS ANTIBAKTERI ACNE PATCH MINYAK ATSIRI DAUN SIRIH (Piper betle L.) TERHADAP Staphylococcus aureus

Acne is a skin condition caused by a buildup of oil in facial pores, which clogs and encourages the growth of bacteria and skin irritation. One of the bacteria in acne is Staphylococcus aureus. Betel leaf essential oil (Piper betle.l) which functions as an antibacterial.
Objective: To determine the effect of differences in concentration on the diameter of the zone of inhibition of antibacterial activity, as well as to determine the antibacterial activity of acne pact preparations against Staphylococcus aureus bacteria using the well method.
Method: This research uses the well method, the well method is used to determine the diameter of the inhibition zone produced against Staphylococcus aureus bacteria.
Results and Conclusions: The acne patch preparation of betel leaf essential oil (Piper betle L) has antibacterial activity against the inhibition zone of Staphylococcus aureus and at a PVA concentration of 7% has the highest inhibition zone (13,79 ± 2,06 ) with the positive control Clindamycin gel 1% was (19,81 ± 1,05).