STUDI PENGGUNAAN ASAM FOLAT PADA PASIEN CHRONIC KIDNEY DISEASE (CKD) DENGAN ANEMIA (Penelitian dilakukan di RSUD dr. Soedomo Trenggalek)

Background: Chronic Kidney Disease is a clinical condition characterized by progressive decline in kidney function, indicated by a glomerular filtration rate (GFR) of less than 60 mL/min per 1.73 m², and is irreversible. Anemia is a common health issue found in patients with chronic kidney disease due to the reduction in erythropoietin hormone, which is related to hemoglobin levels. Folate helps in the synthesis of nucleoproteins and the maintenance of erythropoiesis.
Objective: To determine the pattern of folic acid use in patients with Chronic Kidney Disease and anemia, including dosage, combinations, route of administration, and duration of treatment.
Method: Retrospective observational study using medical record from patients who were hospitalized between 1 January 2023 until 31 December 2023.
Result and Conclusion: Single therapy was used by 7 patients (15%), while combination therapy was used by 39 patients (85%). The most common single therapy was folic acid (3x1mg) p.o, used by 5 patients (11%), and the most common combination therapy was folic acid (3x1mg) p.o. + PRC transfusion (1 unit), used by 18 patients (39%). The swutch pattern has 11 pattren.