SUSANTO, SUSANTO (2008) PENGARUH PEMBERIAN IMMUNOMODULATOR LEVAMISOLPRA VAKSINASI AVIAN INFLUENZA TERHADAP PERTAMBAHAN BOBOT BADAN DAN RESPON KEKEBALAN NON SPESIFIK PADA AYAM PETELUR. Other thesis, University of Muhammadiyah Malang.
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Susanto,2008 the tittle of this research is” the influence of adding turmeric immunomodulator is levamisol effect pre vaccination AI tothe accriotion of body werght and non spesific immune reponse layer This research was help in the experimental farm of animal husbandry and fishenry faculty of muhammadiyah university of malang. The analysis of this research was help in patological laboratory of medikal faculty clinic of muhammadiyah university of malang juni till Agustus 2008. Succes of vaccination to cetain diseases depends of immune response condition. One of drug that can be act as immunomodulator is levamisol. In effort to control Avian Influenza (AI) disease it is necessary to make research to know mechanism of the drug to enhance immune response and accriotion boby werght layer. The purpose of the reseach are to find out levamisol effect pre vaccination AI to non spesific immune reponse layer, histological features of the organ that release immunecompeten cells and haematocrite value as one of indicator of performance of chickens. The research used experimental methode and was based on Randomized Completely Design. One hundred and fifty Days old chicks (DOC) were divided into three groups of treatment. First group was not had levamisole (control group).The second and third group were had levamisol with 1 mg/50 kg body weight respetively for three and six days. Antibody, lymphocyte and bursa fabricius indext were evaluated between two until five weeks after AI vaccination. Lecocyte like monocyte and neutrophyl and haematocrite were examined two days after AI vaccination. Result of the research showed that levamisole treatment pre vaccination AI very significant can increase non specific immune response, remark of increasing monocyte cells. But effect the drug to total of neutrophyle cells not significant. Levamisole treatment pre vaccination AI very significant can increase celluler specific immune response remark of increasing lymphocyte cells. Levamisol treatment did not have significant effect to antibody titer after AI vaccination. Even though numbers of chicks that had high (protectiv) antibody titer level more in group that had levamisole that in group without levamisole. In all of the group there were proliferation of lymphocyte cells. Levamisol treatment did not have significant effect to haematocrite value and no respon accriotion body werght layer Based of the result it is necessary to use levamisole pre vaccination AI (especially secondary vaccination) to increasing immune response chickens to AI infection in nature.
|Item Type:||Thesis (Other)|
|Subjects:||S Agriculture > SF Animal culture|
|Divisions:||Faculty of Agriculture & Animal Husbandry > Department of Animal Scince|
|Depositing User:||Rayi Tegar Pamungkas|
|Date Deposited:||14 Jun 2012 02:29|
|Last Modified:||14 Jun 2012 02:29|
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