Devinta Novi Diana, Eka (2009) EFEK ANTIFUNGI VIRGIN COCONUT OIL TERHADAP CANDIDA ALBICANS. Other thesis, University of Muhammadiyah Malang.
EFEK_ANTIFUNGI_VIRGIN_COCONUT_OIL_TERHADAPCANDIDA_ALBICANS.pdf - Published Version
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Vulvovaginal Candidiasis (VVC) remains generally prominent in the tropic and sub tropic countries. Indeed, 85 to 90 % of VVC causes come from Candida albicans strain. The medications toward VVC have included Ketoconazole, Itraconazole, and Fluconazole. These drugs, however, have unfavorably side effect and high cost, forcing people to search for the utilization of natural substances as the alternative, among other VCO (Virgin Coconut Oil). People expect VCO to give antifungi effect due to its medium chain fatty acid (MCFA) content, involving lauric acid, carpylic acid, capric acid and myristic acid. It works by destructing cell membrane. Research attempts to confirm the VCO’s antifungi effect on the growth of Candida albicans using true experiments Post Test Only Control Group Design. Methods consider diluting tube with six VCO concentrations, i.e. 100 %, 50 %, 25 %, 12.5 %, 6.25%, 3.125%, and 2 controls (material and germ controls) with disc diffusion. Data analysis employs one way ANOVA. Results of research on Minimal Inhibitory Concentration (MIC) cannot be ensured because of turbid color of VCO concentrations at each tube. Minimal Fungicidal Concentration(MFC) seems prominent at concentration 25 %. Inhibitory zone diameter appears found at concentration 100 % (14 mm), 50% (11 mm), 25 % (10 mm), and 12.5 % (8 mm). Results of one way ANOVA test indicate meaningful difference between treatments (p = 0.000). The higher concentration of VCO means the greater capability to prevent and to destroy Candida albicans. The provision of VCO concentrations stimulates the reduction of the number of Candida albicans colony per ml (106). VCO has antifungi effect against the growth of Candida albicans.
|Item Type:||Thesis (Other)|
|Subjects:||R Medicine > R Medicine (General)|
|Divisions:||Faculty of Medicine > Department of Medical Education|
|Depositing User:||Anwar Jasin|
|Date Deposited:||04 Apr 2012 07:59|
|Last Modified:||04 Apr 2012 07:59|
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