EFEK ANALGETIK SARI RIMPANG TEMULAWAK (Curcuma xanthorrhiza Roxb) PADA TIKUS PUTIH (Rattus norvegicus) STRAIN WISTAR

WIDYASARI SUTRISNA, YUNIA (2009) EFEK ANALGETIK SARI RIMPANG TEMULAWAK (Curcuma xanthorrhiza Roxb) PADA TIKUS PUTIH (Rattus norvegicus) STRAIN WISTAR. Other thesis, University of Muhammadiyah Malang.

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Abstract

Painful is inconvenience feeling which felt by patient, so that the sigh represent symptom and sign which not too difficult recognized by klinis but its vary cause (Soelistiono, 2004). Painful if body organ, muscle, or skin injure by, disease, have cram, or swelling (Ikawati, 2008). Temulawak (Curcuma xanthorrhiza Roxb) owning two obstetrical group especial chemistry that is faction compound of kurkumin oil and of atsiri functioning as analgetik, because activity of kurkumin oil and of atsiri can pursue to be formed and prostaglandin of leukotrien. This research aim to to know influence of gist rimpang Curcuma to degradation painful respon at white mouse and to know most effective dose gist rimpang curcuma to degradation painful respond white mouse. Research type is True Experimental Research, research desain is The Pretest-Posstest Control Group Design, measuring painful respon use Analgesy-Meter seen the make-up of burden weight generating painful respon. Population is white mouse male (Rattus norvegicus), amount of sampel 25 tail which consist of 5 treatment group by 5 restating times. Technique intake of sampel is Simple Random Sampling. Variable Research, that is free variable: dose gist rimpang temulawak, varibel depended: degradation of painful respon at white mouse, control variable: white mouse (Rattus norvegicus) strain Wistar male sex, age 2 months, heavy mean body 200 gr, condition of white mouse cage, food and beverage type. Research device use Complete Random Device. Analysis Data with ANAVA and Test of Duncan’S. Result research and result analyse obtained one way varians F count > F tables at level of signifikansi 1% showing there influence of gist dose of rimpang temulawak to degradation painful respon white mouse seen the make-up of burden weight generating painful respon at perception 60 minute after treatment. From result test of Duncan’S 1% gist dose of rimpang curcuma most effective degrade painful respon is white mouse group which given treatment dose 1,67 ml / 200grBB, this result differ reality in comparison with group control without treatment, white mouse group which given treatment of dose 1 ml / 200grBB, and white mouse group which given treatment of dose 1,33 ml/200grBB. This matter prove that gist of rimpang curcuma have an effect on to degradation painful respon at white mouse which measured use Analgesy-Meter.

Item Type: Thesis (Other)
Subjects: Q Science > Q Science (General)
Divisions: Faculty of Teacher Training and Education > Department of Biology Education
Depositing User: Anggit Aldila
Date Deposited: 07 Jul 2012 03:35
Last Modified: 07 Jul 2012 03:35
URI: http://eprints.umm.ac.id/id/eprint/11396

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