STUDI PENGGUNAAN PROTON PUMP INHIBITOR (PPI) PADA PASIEN GERD (Penelitian dilakukan di Instalasi Rawat Inap Rumah Sakit RSU Universitas Muhammadiyah Malang)

Background: Gastroesophageal Reflux Disease (GERD) is a digestive disorder due to the reflux of stomach acid into the esophagus that can reduce the patient's quality of life. The main therapy for GERD is Proton Pump Inhibitor (PPI) because it effectively suppresses gastric acid secretion.
Objective: To determine the pattern of PPI use in GERD patients at the University of Muhammadiyah Malang Hospital, including patient characteristics, risk factors, comorbidities, form of therapy, combination, duration of administration, and achievement of therapy targets.
Methods: This study is an observational study with a descriptive quantitative approach and a retrospective method. Data was obtained through tracing and copying of medical records of GERD patients at the Inpatient Installation of the University of Muhammadiyah Malang Hospital for the period of January-December 2024.
Results and Conclusions: Of the 32 GERD patients, 28 patients received PPI therapy, the majority of GERD patients were women (71%) aged 21–35 years. The dominant risk factors were unhealthy lifestyle (57%), the most comcomorbid diagnosis of hypertension (40%). Therapy patterns included single (30%), combination two (35%), combination three (7%), and alternation therapy (28%). Omeprazole is most commonly used, either alone or in combination with antacids. The duration of administration was 3–5 days (86%), with (92%) patients returning home in improved condition.