UMM Institutional Repository


Devinta Novi Diana, Eka (2009) EFEK ANTIFUNGI VIRGIN COCONUT OIL TERHADAP CANDIDA ALBICANS. Other thesis, University of Muhammadiyah Malang.


Download (85kB) | Preview


Vulvovaginal Candidiasis (VVC) remains generally prominent in the tropic and sub tropic countries. Indeed, 85 to 90 % of VVC causes come from Candida albicans strain. The medications toward VVC have included Ketoconazole, Itraconazole, and Fluconazole. These drugs, however, have unfavorably side effect and high cost, forcing people to search for the utilization of natural substances as the alternative, among other VCO (Virgin Coconut Oil). People expect VCO to give anti­fungi effect due to its medium chain fatty acid (MCFA) content, involving lauric acid, carpylic acid, capric acid and myristic acid. It works by destructing cell membrane. Research attempts to confirm the VCO’s anti­fungi effect on the growth of Candida albicans using true experiments Post Test Only Control Group Design. Methods consider diluting tube with six VCO concentrations, i.e. 100 %, 50 %, 25 %, 12.5 %, 6.25%, 3.125%, and 2 controls (material and germ controls) with disc diffusion. Data analysis employs one way ANOVA. Results of research on Minimal Inhibitory Concentration (MIC) cannot be ensured because of turbid color of VCO concentrations at each tube. Minimal Fungicidal Concentration(MFC) seems prominent at concentration 25 %. Inhibitory zone diameter appears found at concentration 100 % (14 mm), 50% (11 mm), 25 % (10 mm), and 12.5 % (8 mm). Results of one way ANOVA test indicate meaningful difference between treatments (p = 0.000). The higher concentration of VCO means the greater capability to prevent and to destroy Candida albicans. The provision of VCO concentrations stimulates the reduction of the number of Candida albicans colony per ml (106). VCO has antifungi effect against the growth of Candida albicans.

Item Type: Thesis (Other)
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine > Department of Medicine (11201)
Depositing User: Anwar Jasin
Date Deposited: 04 Apr 2012 07:59
Last Modified: 04 Apr 2012 07:59

Actions (login required)

View Item View Item
UMM Official

© 2008 UMM Library. All Rights Reserved.
Jl. Raya Tlogomas No 246 Malang East Java Indonesia - Phone +62341464318 ext. 150, 151 - Fax +62341464101
E-Mail : - Website : - Online Catalog : - Repository :

Web Analytics

UMM Institutional Repository is powered by :
EPrints Logo