FORMULASI DAN UJI IRITASI SEDIAAN SABUN MANDI CAIR EKSTRAK PEPAYA (Carica papaya L.) BERBASIS SURFAKTAN DENGAN METODE HET-CAM

Background: Papaya extract has the best antioxidant effect because it contains compounds such as papain, flavonoids, alkaloids, saponins, glycosides and phenols. Flavonoids function as strong antioxidants and protect the body against free radicals. The use of liquid soap preparations needs to be tested for safety using the HET-CAM irritation test method.
Objective: To determine the irritation effect of liquid soap preparations with carica papaya extract at levels 2%, 4%, 6% using the HET-CAM method.
Methods: This research is an experimental research which first makes a liquid soap preparation with the active ingredient papaya extract in concentrations of 2%, 4% and 6%, then an irritation test is carried out using the HET-CAM method.
Results and Conclusions: Based on the research results, it can be concluded that liquid soap preparations with the active ingredient papaya extract 2%, 4% and 6% cause an irritating effect which was tested using the HET-CAM method.