EFEK EKSTRAK APEL (MALUS DOMESTICA) TERHADAP KONTRAKTILITAS OTOT POLOS ILEUM MARMUT (CAVIA PORCELLUS) DIINDUKSI HISTAMIN

ARIESKI HAZANIE, DEDDY (2009) EFEK EKSTRAK APEL (MALUS DOMESTICA) TERHADAP KONTRAKTILITAS OTOT POLOS ILEUM MARMUT (CAVIA PORCELLUS) DIINDUKSI HISTAMIN. Other thesis, University of Muhammadiyah Malang.

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Abstract

Empirically, apple can be used to cure diarrhea, but it is still needed to be proven scientifically. This study aims at proving whether or not apple extract (Malus domestica) could cause contraction decrease on the tissue of tendon of marmot’s ileum contraction (Cavia porcellus) inducted by histamin. This is a purely experimental research by means of the Posttest Control Group Design. The samples were 5 marmot’s which were then classified into four groups. The first group was treated as control group in which we did not give any apple extract but histamine only. On the other hand, the second, the third, and the fourth groups were treated at the same way by giving apple extract about 0,032 %, 0,062 % and 0,118 %. The parameter measured in this study was how much the contraction decrease of the tissue of tendon of marmot’s ileum. The research finding showed about the second group (EA 0,032%) with mean contraction decrease are 19,00; the third group are 29,16; the fourth group are 36,00. The research finding showed that the giving of apple extract could significantly minimize the contraction on the tendon of marmot’s ileum (ANOVA, p = 0,000), and there was strong and significant relationship between apple extract and the contraction decrease (r=0,868 and p=0,00). The second groups, the third groups, and the fourth groups are minimized contraction on tendon of marmot’s ileum was caused by the active effect on substances in apple extract, that was quercetin. In conclusion, itwas empirically proven that apple extract could minimize the contraction power of tendon of marmot’s ileum.

Item Type: Thesis (Other)
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine > Department of Medical Education
Depositing User: Anwar Jasin
Date Deposited: 21 Mar 2012 14:36
Last Modified: 21 Mar 2012 14:36
URI: http://eprints.umm.ac.id/id/eprint/874

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