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PENGARUH EKSTRAK KURMA (Phoenix Dactylifera) VARIETAS ‘AJWA TERHADAP KADAR KREATININ DAN UREUM SERUM TIKUS PUTIH JANTAN GALUR WISTAR YANG DIINDUKSI KOTRIMOKSAZOL

khaerunnisah, khaerunnisah (2020) PENGARUH EKSTRAK KURMA (Phoenix Dactylifera) VARIETAS ‘AJWA TERHADAP KADAR KREATININ DAN UREUM SERUM TIKUS PUTIH JANTAN GALUR WISTAR YANG DIINDUKSI KOTRIMOKSAZOL. Undergraduate (S1) thesis, University of Muhammadiyah Malang.

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Abstract

Background: Date palm extract contains lots of Flavonoids and Phenolics as the antioxidant which can be used to prevent acute kidney disease. Cotrimoxazole is a medication with a certain dosage can cause acute kidney disease. Objective: To find out the effect of date palm extract (Phoenix Dactylifera) Ajwa varieties on Creatinine and Ureum Serum of white male wistar rat induced by Cotrimoxazole. Method: True experimental with post test control group design approaches. White male wistar rat as the sample which is divided into 5 groups (negative control group, positive control group, treatment 1,2 and 3). The negative control group was given food and drink only, positive control group induced by cotrimoxazole during 10 days, treatment group 1,2 and 3 was given cotrimoxazole during 10 days and induced by date palm extract with multilevel dosages during 14 days. Discussion and Results: ANOVA tests showed no significant differences of Ureum Serum among the groups (p=0,062). There were no significant differences caused by the factors of food and stressfulness. Whereas in Creatinine levels obtained significant differences (p=0,002). However, there is a reduction in Creatinine levels of positive group control (+), likely caused by muscle mass factor, error while giving the medication theough oral feeding tube, and the amount of body fluids. Conclusion: Ajwa date palm extract does not give significant effect towards Ureum levels. However, give significant effevt towards white male wistar rat which induced by Cotrimoxazole

Item Type: Thesis (Undergraduate (S1))
Student ID: 201610330311195
Thesis Advisors: dr. Diah Hermayanti, Sp.PK (0016126601), dr. Andi Abdillah, Sp.B FINACS FICS (0712067601)
Keywords: Date Palm Extract, Acute Kidney Disease, Ureum Levels, Creatinine Levels.
Subjects: R Medicine > RC Internal medicine
Divisions: Faculty of Medicine > Department of Medicine (11201)
Depositing User: 201610330311195
Date Deposited: 29 Jan 2020 03:04
Last Modified: 29 Jan 2020 03:04
URI : http://eprints.umm.ac.id/id/eprint/58661

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