UJI EFEKTIVITAS EKSTRAK HERBA MENIRAN (Phyllantus niruri L.) SEBAGAI HEPATOPROTEKTOR TERHADAP KADAR BILIRUBIN TOTAL SERUM TIKUS PUTIH (Rattus norvegicus)

NAFISAH, AINUN (2008) UJI EFEKTIVITAS EKSTRAK HERBA MENIRAN (Phyllantus niruri L.) SEBAGAI HEPATOPROTEKTOR TERHADAP KADAR BILIRUBIN TOTAL SERUM TIKUS PUTIH (Rattus norvegicus). Other thesis, University of Muhammadiyah Malang.

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Abstract

Liver or hepar is one of the very complex and all important organ in metabolism in body. Liver often become target organ because getting mixed up with chemical metabolism which have the character of toxic and also free radical. the free radical and toxic chemical can cause damage of cell, network, macromolecules and also membrane. Activity of the free radical can be weakened by existence of an antioksidan. Basically hepar the functioningness as system defence of body it is of course also have antioksidan the good enoughness, however caused by hit liver shares free radical hence liver activity not maximal, so that require to be given by antioksidan coming from outside body. In so many plant medicinize a lot of consisting in vitaminses able to share antioksidan one of them is Meniran ( Phyllantus Niruri L.). Active Compound at meniran which is have potency as antioksidan is flavonoid. Intention of this research is to know effect of extract herba meniran in normal rate bilirubin total of white mouse serum and to know extract concentration of herba meniran which is effective peling in normal rate bilirubin total of white mouse serum which induceed by CCL4. This Research have the character of True Experiment of Research ( real research) by using Complete Random Device ( divided RAL) to become 5 treatment and 5 restating, that is ; Normal ( I), CCL4 ( II), Extract of Herba Meniran dose 5 + CCL4 ( III), Extract of Herba Meniran dose 10 + CCL4 ( IV), and also extract of herba dose meniran 15 + CCL4 ( V). Analysis Data which used in this research is; Test of Normalitas, Test Homogeneity, Test one way ANAVA and Test of Duncan with level 5%. obtained result of this research indicate that extract of herba meniran with dose 5%, ! 0% and 15% can degrade again rate of bilirubin white mouse serum which induceed by CCL4. Pursuant to Test of Duncan 5%, can know that extract concentration of herba most effective meniran in degrading rate of bilirubin white mouse serum is dose 15%. Thereby, in this research can be proved that Extract herba meniran can degrade again rate of bilirubin total of white mouse serum which induceed by CCL4.

Item Type: Thesis (Other)
Subjects: Q Science > Q Science (General)
Divisions: Faculty of Teacher Training and Education > Department of Biology Education
Depositing User: Anggit Aldila
Date Deposited: 19 May 2012 03:43
Last Modified: 19 May 2012 03:43
URI: http://eprints.umm.ac.id/id/eprint/5545

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