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PENGARUH KADAR POLIPLASDON TERHADAP MUTU FISIK TABLET EKSTRAK SARANG SEMUT (Myrmecodia pendans)

Janah, Sirotul (2019) PENGARUH KADAR POLIPLASDON TERHADAP MUTU FISIK TABLET EKSTRAK SARANG SEMUT (Myrmecodia pendans). Bachelors Degree (S1) thesis, University of Muhammadiyah Malang.

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pendahuluan.pdf

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BAB I.pdf

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Abstract

Background: Myrmecodia pendans is one of the plants that has many medical benefits, one of which is antidiabetic. This plant is consumed with a simple method as a herbal tonic and capsules. In this research, Myrmecodia pendans extract tablet formula was developed that meets the standardized requirements. Research Objectives: The purpose of this study was to determine the effect of addition of 1%, 3%, and 5% polyplasdon level on the physical quality of Myrmecodia pendans extract tablets and determine which formula able to form tablets that meet the standardized requirements. Method: Myrmecodia pendans extract was made by kinetic maceration using 96% ethanol as solvent and the tablet was made by wet granulation method with the addition of polyplasdon as desintegran material. Granule examination includes flowability and angle of repose, moisture content, compressibility, fines quantity, and compactibility. While the physical quality test of the tablets include hardness, friability, and dissolution time of the tablet which then analyzed statistically. Results and Conclusions: The results of this study showed that greater levels of polyplasdon resulted in a decrease of hardness and dissolution time. On the other hand it had an effect of increase the fragility of tablets. Statistical analysis showed a significant difference. The best result of Myrmecodia pendans extract tablet is obtained from formula of 1% polyplasdon level.

Item Type: Thesis (Bachelors Degree (S1))
Student ID: 201410410311110
Thesis Advisors: Achmad Radjaram (0028084902), Dian Ermawati (11209070481)
Keywords: Myrmecodia pendans, Polyplasdon, Wet Granulation, Tablet
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Health Science > Department of Pharmacy (48201)
Depositing User: 201410410311110
Date Deposited: 07 Nov 2019 04:07
Last Modified: 07 Nov 2019 04:07
URI : http://eprints.umm.ac.id/id/eprint/54880

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