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STUDI PENGGUNAAN ANTIBIOTIK GOLONGAN FLUOROKUINOLON PADA PASIEN INFEKSI SALURAN KEMIH (Penelitian Dilakukan di RSU Dr. Saiful Anwar Malang)

Claudia, Annisa (2019) STUDI PENGGUNAAN ANTIBIOTIK GOLONGAN FLUOROKUINOLON PADA PASIEN INFEKSI SALURAN KEMIH (Penelitian Dilakukan di RSU Dr. Saiful Anwar Malang). Undergraduate (S1) thesis, University of Muhammadiyah Malang.

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Abstract

Urinary Tract Infection (UTI) is defined as the presence of microorganisms in the urinary tract that generally characterized by 105 bacteria/mL in the urine. The goal of UTI treatment is to eradicate infectious bacteria, prevent or treat systemic consequences, and prevent recurrence of infection. So that antimicrobial administration is the basis for UTI treatment. Fluoroquinolones have a broad spectrum of activity, can penetrate tissues and reach levels that are good in the urinary and systemic tract so that they are the drug of choice for empirical treatment of uncomplicated pyelonephritis and complicated UTIs. Objective: The study aims to determine the pattern of use including type of dosage, dosage form, route of administration, interval of administration, frequency and duration of use of Fluoroquinolones in UTI patients hospitalized at Dr. Saiful Anwar Malang for the period January 2018-December 2018. Research Method: Observational study with descriptive and retrospective method. Conclusion: The single use of Fluoroquinolone group antibiotics was 33 patients (73%) and the combination was 12 patients (27%). The most common use of single antibiotics of the Fluoroquinolone group was Ciprofloxacin (2x400mg) IV in 19 patients (58%) and Ciprofloxacin (2x200mg) IV in 8 patients (24%). The most widely used combination therapy was Ciprofloxacin (2x400mg) IV + Ceftriaxone (2x1g) IV in 5 patients (45%). Most antibiotic switch patterns are dose changes (28%) and drug changes (28%) in the Fluoroquinolones and changes in single administration into a combination (28%).

Item Type: Thesis (Undergraduate (S1))
Student ID: 201510410311028
Thesis Advisors: Hidajah Rachmawati (0713127102), Didik Hasmono (1195809111986011001)
Keywords: Fluoroquinolone, UTI, Inpatients
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Health Science > Department of Pharmacy (48201)
Depositing User: 201510410311028
Date Deposited: 16 Oct 2019 06:07
Last Modified: 16 Oct 2019 06:07
URI : http://eprints.umm.ac.id/id/eprint/53912

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