EFEK EKSTRAK BUAH MENGKUDU (Morinda citrifolia L.) SEBAGAI ANTIMIKROBA TERHADAP Staphylococcus aureus

AMBAR SARI, KHALIFENTI (2010) EFEK EKSTRAK BUAH MENGKUDU (Morinda citrifolia L.) SEBAGAI ANTIMIKROBA TERHADAP Staphylococcus aureus. Other thesis, University of Muhammadiyah Malang.

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Abstract

Background: Staphylococcus aureus the most common bacterial pathogens in human body. Resistance of Staphylococcus aureus to antibiotics increasing, thus plant metabolite is necessary for the alternatives treatment. Morinda citrifolia L fruit is alleged that has antimicrobial effects as containing several active substances, which works by damaging the cell wall, cytoplasmic membrane and inhibits the synthesis protein on ribosomes. Objective: This study was intended to prove the antimicrobial effects of extracts fruit Morinda citrifolia L against Staphylococcus aureus. Methods: This study employed the “True Experiments Post Test Only Control Group Design”. The method used was tube dilutions containing different concentration of noni fruit extract; 100%, 50%, 25%, 12.5%, 6.25%, 3.125%, 1.56%, 0.78% and two controls (material and germ controls) . Data obtained were analyzed by using one­way ANOVA, regression and correlation .Results: The concentration of Minimal Inhibitory Concentration (MIC) awas determine in 6.25%. Minimal Bactericidal Concentration (MBC) 12.5%. The results will show a significant differences between treatments (p = 0000). Higher concentration of extracts Morinda citrifolia L fruit can reduce coloni number of staphylococcus aureus (p<0.01; r=­0.909). Morinda citrifolia L concentration of fruit extracts affect the reduction of Staphylococcus aureus bacterial colonies R2 = 82.6%. the higher Morinda citrifolia wider ability to make inhibisi zone (r=0,9111; p=0,000<0,01) Conclusions : Morinda citrifolia L fruit extracts have antimicrobial effects on the growth of Staphylococcus aureus.

Item Type: Thesis (Other)
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine > Department of Medical Education
Depositing User: Anwar Jasin
Date Deposited: 16 Mar 2012 13:46
Last Modified: 16 Mar 2012 13:46
URI: http://eprints.umm.ac.id/id/eprint/511

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