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STUDI PENGGUNAAN FUROSEMID PADA PASIEN SINDROM NEFROTIK (Penelitian Dilakukan di RSUD Dr. Saiful Anwar Malang)

Laily, Richa Faidhatul (2019) STUDI PENGGUNAAN FUROSEMID PADA PASIEN SINDROM NEFROTIK (Penelitian Dilakukan di RSUD Dr. Saiful Anwar Malang). Bachelors Degree (S1) thesis, University of Muhammadiyah Malang.

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Abstract

Background: Nephrotic syndrome is a condition where there is loss of excessive protein into urine due to glomerular filtration disorders with complex symptoms of proteinuria (>3,5 g/ 24 hours), hypoalbuminemia, edema, and hyperlipidemia. Furosemide is a strong diuretic (loop diuretic) used to treat edema in patients with nephrotic syndrome. The mechanism action of furosemide is inhibit the NA+/K+/Cl2- cotransporter, thus hinders water reabsorption in the nephron by obstructing the sodium-pottasium-chloride reseptors in the thick ascending limb of loop of henle. Objective: This study is to determine the pettern of using furosemide in patients with nephrotic syndrome at Dr. Saiful Anwar General Hospital of Malang. Method: Retrospective observational in patients with nephrotic syndrome at Dr. Saiful Anwar General Hospital of Malang from January – Desember 2018. Results and Conclusions: The use single of furosemide in 43 patients (91%) and a combination of two in 4 patients (9%). The most common use of single furosemide is furosemide (1×40 mg) iv in 5 patients (12%). The use of two combination without switch is furosemide (1×40 mg) po with spironolakton (1×50 mg) po in 1 patient. The pattern of switching furosemide therapy with 2 patterns in 6 patients (55%), 3 patterns in 4 patients (36%), and 6 patterns in 1 patient (9%).

Item Type: Thesis (Bachelors Degree (S1))
Student ID: 201510410311149
Thesis Advisors: Hidajah Rachmawati (11406090449), Didik Hasmono (195809111986011011)
Keywords: Furosemide, Nephrotic Syndrome, Hospitalization
Subjects: R Medicine > RM Therapeutics. Pharmacology
Divisions: Faculty of Health Science > Department of Pharmacy (48201)
Depositing User: 201510410311149
Date Deposited: 15 Aug 2019 04:51
Last Modified: 15 Aug 2019 04:51
URI : http://eprints.umm.ac.id/id/eprint/48946

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