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STUDI PENGGUNAAN OBAT GOLONGAN STATIN PADA PASIEN SINDROM NEFROTIK (Penelitian Dilakukan di Rumah Sakit Umum Daerah Dr. Saiful Anwar Malang)

Norahman, Rian (2019) STUDI PENGGUNAAN OBAT GOLONGAN STATIN PADA PASIEN SINDROM NEFROTIK (Penelitian Dilakukan di Rumah Sakit Umum Daerah Dr. Saiful Anwar Malang). Undergraduate (S1) thesis, University of Muhammadiyah Malang.

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Abstract

Background: NS or nephrotic syndrome is a complex set of symptoms consisting of proteinuria, hypoalbuminemia, edema, and hyperlipidemia. Statins is a first-line treatment used to reduce cholesterol in patients with nephrotic syndrome. The cholesterol-lowering activity of the statin group was associated with inhibiting competitive HMG-CoA reductase enzyme. In addition to cholesterol-lowering activity, statins also have pleiotropic effects that can improve endothelial function. Objective: To determine the pattern of statin drug use in patients with nephrotic syndrome at the Regional General Hospital Dr. Saiful Anwar Malang from the period of January 1 to December 31, 2018. Methods: The study was conducted on nephrotic syndrome patients with a retrospective descriptive observational method at the Regional General Hospital Dr. Saiful Anwar Malang from the period of January 1 to December 31, 2018. Results and Conclusions: The use pattern of statin given by monotherapy in all patients with simvastatin in 29 patients (88%) and atorvastatin in 4 patients (12%). The dose of simvastatin (1x20 mg) po was used the most in 28 patients (85%).

Item Type: Thesis (Undergraduate (S1))
Student ID: 201510410311133
Thesis Advisors: Didik Hasmono (195809111986011011), Hidajah Rachmawati (11406090449)
Keywords: Statin, Simvastatin, Atorvastatin, Nephrotic syndrome
Subjects: R Medicine > RM Therapeutics. Pharmacology
Divisions: Faculty of Health Science > Department of Pharmacy (48201)
Depositing User: 201510410311133
Date Deposited: 15 Aug 2019 02:18
Last Modified: 15 Aug 2019 02:18
URI : http://eprints.umm.ac.id/id/eprint/48895

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