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UJI KARAKTERISTIK FISIK DAN AKTIVITAS ANTIBAKTERI GEL EKSTRAK ETANOL BAWANG DAYAK Eleutherine palmifolia (Terhadap Pseudomonas aeruginosa)

Kusumawardani, Ayu (2019) UJI KARAKTERISTIK FISIK DAN AKTIVITAS ANTIBAKTERI GEL EKSTRAK ETANOL BAWANG DAYAK Eleutherine palmifolia (Terhadap Pseudomonas aeruginosa). Undergraduate (S1) thesis, University of Muhammadiyah Malang.

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Abstract

Background : Pseudomonas aeruginosa is a bacterium that is an opportunistic pathogen. Ethanol extract of Dayak onion has antibacterial activity against the bacterium Pseudomonas aeruginosa. Formulated in a gel dosage form because it is easily applied, comfortable to use on the skin, and provides a cool sensation. Objective : To determine the effect of Dayak onion ethanol extract levels with concentrations of 2%, 4%, and 6% on physical characteristics and to determine the antibacterial activity of Pseudomonas aeruginosa from the preparation of Dayak onion ethanol extract gel. Method : The ethanol extract of dayak onions was formulated into gel in 3 formulas, namely FI (2%), FII (4%), and FIII (6%). Tested physical characteristics including organoleptic, pH, viscosity, homogeneity. The antibacterial activity test was tested by the well diffusion method. Result and Conclusion : The organoleptic test of the three dayak onion ethanol extract gel formulas has a soft texture, distinctive smell, Formula 1 has a brownish red (clear), Formula II is brownish red (thick), Formula III is brown. Based on the One-Way Anova statistical analysis shows a significant difference for the evaluation of viscosity and dispersion. In the antibacterial test the inhibition did not appear at the extract concentration of 2%, but at concentrations of 4% (10mm), and 6% (12 mm) there were inhibitory zones. The concentration of 6% has antibacterial activity better than the concentrations of 2% and 4%.

Item Type: Thesis (Undergraduate (S1))
Student ID: 201510410311038
Thesis Advisors: Uswatun Chasanah (0703086702), Dian Ermawati (0707028102)
Keywords: Ethanol extract of onion dayak, Pseudomonas aeruginosa, Gel, Antibacterial.
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Health Science > Department of Pharmacy (48201)
Depositing User: 201510410311038
Date Deposited: 14 Aug 2019 04:41
Last Modified: 14 Aug 2019 04:41
URI : http://eprints.umm.ac.id/id/eprint/48796

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