UMM Institutional Repository

Pengaruh Ekstrak Buah Mengkudu (Morinda Citrifolia) Terhadap Diameter Sel Langerhans Tikus Putih (Rattus Novergicus Strain Wistar) Yang Di Induksi Streptozotocin

Jannah, Anina Ni'matul (2019) Pengaruh Ekstrak Buah Mengkudu (Morinda Citrifolia) Terhadap Diameter Sel Langerhans Tikus Putih (Rattus Novergicus Strain Wistar) Yang Di Induksi Streptozotocin. Bachelors Degree (S1) thesis, University of Muhammadiyah Malang.

[img]
Preview
Text
PENDAHULUAN.pdf

Download (704kB) | Preview
[img]
Preview
Text
BAB 1.pdf

Download (265kB) | Preview
[img]
Preview
Text
BAB 2.pdf

Download (743kB) | Preview
[img]
Preview
Text
BAB 3.pdf

Download (278kB) | Preview
[img] Text
BAB 4.pdf
Restricted to Registered users only

Download (409kB) | Request a copy
[img] Text
BAB 5.pdf
Restricted to Registered users only

Download (600kB) | Request a copy
[img] Text
BAB 6.pdf
Restricted to Registered users only

Download (271kB) | Request a copy
[img] Text
BAB 7.pdf
Restricted to Registered users only

Download (235kB) | Request a copy
[img] Text
LAMPIRAN.pdf
Restricted to Registered users only

Download (1MB) | Request a copy

Abstract

Jannah, Anina Ni’matul. 2019, Effect of Noni Fruit Extract (Morinda citrifolia) on Langerhans Cell Diameter of White Rat (Rattus novergicus strain wistar) induced by Streptozotocin. Final Assignment of Medical Faculty of Muhammadiyah Malang University. Advisors : (I) dr. Dian Yuliarta Lestari, Sp.PA (II) dr. Gita Sekar Prihanti, M.Pd.Ked Background: Hyperglycemia accelerate the increasing of ROS production and cause many pancreatic cells damage inducing oxydative stress and reduce the diameter of langerhans’ cell. Noni fruit has a hypoglycemic effect and antioxidant activity which is able to regenerate beta cells damage and followed by increasing the diameter of Langerhans’ cells Objective: To determine the effect of noni fruit extract (Morinda citrifolia) on Langerhans cell’s diameter of white rat (Rattus novergicus strain wistar) induced by streptozotocin Method: True Experiment with Post test-only control group design. 16 rats as a sample were divided into 4 groups: control group (STZ 60 mg/kgBW), Extract with dose of 50, 100, 200 mg/kgBW for 25 days. Measurement of Langerhans cell diameter using Image Raster software 3. The data were analyzed by using test One-Way ANOVA, Post Hoc Bonferroni test and regression test. Result and Discussion: One-Way ANOVA results showed the data of all treatment groups were significant (P<0.05). This experiment showed that 50mg/KgBW was the dose that starts for give an effect to Langerhans’ diameter. Regression test results indicated that Noni fruit’s extract had an effect of 62.5% on Langerhans’ cell diameter (R2=0.625). This was probably due to antioxidant compounds such as flavonoids and alkaloids at noni fruit Conclusion: Noni fruit’s extract shows a significant effect on the diameter of Langerhans’ cell white rat Keyword: Hyperglycemia, Diameter of Langerhans’ Cell, Pancreas, Noni fruit

Item Type: Thesis (Bachelors Degree (S1))
Student ID: 201510330311088
Corporate Creators: Dian Yuliarta Lestari, Gita Sekar Prihanti
Keywords: Hyperglycemia, Diameter of Langerhans’ Cell, Pancreas, Noni fruit
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine > Department of Medicine (11201)
Depositing User: 201510330311088
Date Deposited: 15 Jul 2019 09:28
Last Modified: 15 Jul 2019 09:28
URI : http://eprints.umm.ac.id/id/eprint/47026

Actions (login required)

View Item View Item
UMM Official

© 2008 UMM Library. All Rights Reserved.
Jl. Raya Tlogomas No 246 Malang East Java Indonesia - Phone +62341464318 ext. 150, 151 - Fax +62341464101
E-Mail : infopus[at]umm.ac.id - Website : http://lib.umm.ac.id - Online Catalog : http://laser.umm.ac.id - Repository : http://eprints.umm.ac.id

Web Analytics

UMM Institutional Repository is powered by :
EPrints Logo