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OPTIMASI FORMULASI KRIM EKSTRAK ETANOL BUNGA MARIGOLD (Tagetes erecta L.) SEBAGAI ANTIOKSIDAN (dengan konsentrasi 4%, 6%, dan 8%)

Agustina, Nailah (2018) OPTIMASI FORMULASI KRIM EKSTRAK ETANOL BUNGA MARIGOLD (Tagetes erecta L.) SEBAGAI ANTIOKSIDAN (dengan konsentrasi 4%, 6%, dan 8%). Bachelors Degree (S1) thesis, University of Muhammadiyah Malang.

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Abstract

Background: Free radicals are destructive to interact inside the body by oxidation with certain body cells so that trigger a variety of ailments such as premature aging. Marigold’s flower contains lutein which function as antioxidants so that made ethanol extracts of marigold flowers cream that acts as an antioxidant. Objective: To know the physical characteristics of the material of the cream made 3 formula with the variation of levels of ethanol extract marigold’s flower; F1 (4%), F2 (6%), and F3 (8%) (organoleptis, viscosity, pH, and the spread of power) as well as knowing the type of emulsion in cream preparations, to know the stability of preparations, and aware of the effectiveness of antioxidants on extract and ethanol extract cream preparations of marigold flowers. Test method: Organoleptis test, DPPH observed visually, emulsion-type test, test the pH, viscosity testing, test the power spread and test the stability of the preparations done test freeze thaw for 6 cycles were analyzed using the statistical test method is one way-annova. Results and conclusion: The material of ethanol extract of marigold flowers cream on all formula has ocher, soft texture, and the smell of marigold’s floral with emulsion type results M/a. results of the statistical tests with annova one-way method, obtained the results of pH ( 6,94-7,31), viscosity (14333,33-18500 cPs) while in power test scatterplot (0,0261-0,0653). Ethanol extracts of marigold flowers have an IC50 of 31.87 ppm, which can be summed up as very active antioxidants. Ethanol extracts of marigold flowers cream on formula 1 brings about IC50 874.90 ppm; Formula 2:758.17 ppm, and formula 3:597.33 ppm which suggest that ethanol extracts of marigold flowers cream has antioxidant power that is not active. On test freeze thaw, preparations from pH decline earlier.

Item Type: Thesis (Bachelors Degree (S1))
Student ID: 201410410311031
Keywords: Ethanol Extracts Of Marigold’s Flower, Antioxidant’s Cream, DPPH
Subjects: R Medicine > RZ Other systems of medicine
Divisions: Faculty of Health Science > Department of Pharmacy (48201)
Depositing User: Nurhadin Nurhadin
Date Deposited: 26 Dec 2018 04:21
Last Modified: 26 Dec 2018 04:21
URI : http://eprints.umm.ac.id/id/eprint/42577

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