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UJI AKTIVITAS ANTIBAKTERI FRAKSI ETANOL KULIT BUAH Citrus reticulata TERHADAP PERTUMBUHAN Staphylococcus aureus MENGGUNAKAN METODE DIFUSI CAKRAM

Hidayat, Rahmat (2018) UJI AKTIVITAS ANTIBAKTERI FRAKSI ETANOL KULIT BUAH Citrus reticulata TERHADAP PERTUMBUHAN Staphylococcus aureus MENGGUNAKAN METODE DIFUSI CAKRAM. Bachelors Degree (S1) thesis, University of Muhammadiyah Malang.

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Abstract

Background : Infection disease is one of the most disease with high prevalencies in developing country, include Indonesia. One cause of infectious disease is Staphylococcus aureus bacteria which is a normal flora which can become a pathogen in the body. To overcome the infectious disease are used synthetic and chemical drugs that can lead to antibiotic resistance from overuse. Therefore it is necessary a natural alternative medicine from plants. Citrus reticulata is known to has activities such as antimutagenic, anti-inflammatory, antioxidant, antitumor, anti atherosclerosis and antibacterial. Objective : This study aimed to observe the antimicrobial activities of ethanol fraction of the peel fruit Citrus reticulata toward Staphylococcus aureus bacterial growth with disk diffusion method. Method : Antibacterial activity assay using disk diffusion method. Ethanol fraction of peel fruit Citrus reticulata was processed by immersion maceration in order to separate the polar molecule which concentration 5%, 10% and 25 for Staphylococcus aureus bacterial. Result and Conclusion : The ethanol fraction of peel fruit Citrus reticulata has antibacterial activity toward Staphylococcus aureus bacterial growth with concentration 5% b/v (3.500 μg/disc) is 7,31 mm; 10% b/v (7.000 μg/disc) is 10,24 mm and 25% b/v (17.500 μg/disc) is 13,75 mm. The result rising of concentration rising the clear zone and more poten to Gram positive bacteria (Staphylococcus aureus).

Item Type: Thesis (Bachelors Degree (S1))
Student ID: 201410410311023
Keywords: Antibacterial, Citrus reticulata, Ethanol fraction, Disk diffusion, Staphylococcus aureus.
Subjects: R Medicine > RZ Other systems of medicine
Divisions: Faculty of Health Science > Department of Pharmacy (48201)
Depositing User: Nurhadin Nurhadin
Date Deposited: 06 Dec 2018 03:18
Last Modified: 06 Dec 2018 03:18
URI : http://eprints.umm.ac.id/id/eprint/41546

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