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UJI AKTIVITAS MUKOLITIK FRAKSI ETANOL DAUN Lantana camara Linn SECARA IN VITRO

Dwi Fariyana, Wiraningtyas (2018) UJI AKTIVITAS MUKOLITIK FRAKSI ETANOL DAUN Lantana camara Linn SECARA IN VITRO. Bachelors Degree (S1) thesis, University of Muhammadiyah Malang.

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Abstract

Background: Lantana camara is well known to cure several diseases and used in various folk medicinal preparations. It is one of medicinal plants that has been used empirically as cough medicine. However, the use of Lantana camara as cough treatment has not proved yet a lot by scientist. Aim: The aim of this study was to examine the effect of Lantana camaraleaves as a productive cough medicine (mucolytic activity) by ethanolic fraction. Methods:This study used a true experimental and post-test group design. It was tested by several concentrations i.e. 0.1%, 0.5%, and 1%, in 20% cow’s mucous. The mucolytic activity was tested using Ostwald® viscometer, and 0.1% Acetylcysteine as positive control. Results: Phytochemical screening results showed that Lantana camara leaf ethanolic fraction contains Saponin, Steroid/Terpenoid, and Tannin. The results showed that Lantana camara leaf ethanolic fraction with 0,1%, 0.5%, and 1% using oneway ANOVA having significant 0.000 (P<0.005). The percentage of mucolytic effect also showed that the trend was downward. It means that Lantana camara leaf ethanolic fraction did not have mucolytic activity. Conclusion: The study revealed that ethanolic fraction of Lantana camara leaf has no mucolytic activity and it has no potential to be developed as a traditional medicine for productive cough treatment.

Item Type: Thesis (Bachelors Degree (S1))
Student ID: 201410410311204
Thesis Advisors: University of Muhammadiyah Malang
Keywords: Medicinal plant, Lantana camara, Mucolytic, Etanolic Fraction, productive cough
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Health Science > Department of Pharmacy (48201)
Depositing User: Nurhadin Nurhadin
Date Deposited: 04 Dec 2018 01:32
Last Modified: 04 Dec 2018 01:32
URI : http://eprints.umm.ac.id/id/eprint/41337

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