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UJI AKTIVITAS ANTIINFLAMASI FRAKSI N-HEKSAN DARI DAUN Jatropha gossypifolia L. TERHADAP Rattus novergicus YANG DIINDUKSI KARAGENIN

Hasbullah, Hasbi Sacitra s. (2018) UJI AKTIVITAS ANTIINFLAMASI FRAKSI N-HEKSAN DARI DAUN Jatropha gossypifolia L. TERHADAP Rattus novergicus YANG DIINDUKSI KARAGENIN. Bachelors Degree (S1) thesis, University of Muhammadiyah Malang.

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Abstract

Background: Jatropha gossypifolia L. is one of the plants that has potential as anti-inflammatory. It leaves contain is flavonoid, terpenoid and anthraquinone. Objective: The aim of this study is to obtain anti-inflammatory activity data form Jatropha gossypifolia L. n-hexane fraction to decrease in the oudem volume / decrease inflammatory in rat induced carragenin. Methods: The research method which used to test the inflammatory activity are by measure the oudem volume using pletsmometer. The extract were tested are obtained of kinetic maceration. Then the animals were divide to 5 group. Positive control – negative control. Test group one by 100 mg/Kg BB, group two 200 mg/Kg BB and group three 300 mg/Kg BB. Results and Conclusion: The result obtained from this study is the compound which is found in Jatropha gossypifolia L. n-hexane fraction is flavonoid, terpenoid and anthraquinone. Percentage of udem decrease are 32 % for control group positive (na diklofenak), 11 % for dose 100 mg/Kg BB, 24 % for dose 200 mg/Kg BB and 20 % for dose 300 mg/Kg BB in the 150, 120, 150, and 90 minutes. The results of statistical tests with one way anova and post hoc tuckey showed all groups test Jatropha gossypifolia L. n-hexane fraction having the difference significantly (P<0.05) of control negative and having no distinction significantly (P>0.05) and control positive.

Item Type: Thesis (Bachelors Degree (S1))
Student ID: 201110410311131
Keywords: N-hexane fraction, Jatropha gossypifolia L., Eupharbiceae, Flavonoid, Antiinflamasi, Rattus novregicus, One Away ANOVA
Subjects: R Medicine > RZ Other systems of medicine
Divisions: Faculty of Health Science > Department of Pharmacy (48201)
Depositing User: Nurhadin Nurhadin
Date Deposited: 23 Nov 2018 07:28
Last Modified: 23 Nov 2018 07:28
URI : http://eprints.umm.ac.id/id/eprint/40698

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