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FORMULASI TABLET HISAP EKSTRAK PEGAGAN (Centella asiatica L.) DENGAN BASIS MANITOL (Pengaruh Kadar Pengikat PVP K-30 Terhadap Mutu Fisik Tablet)

WIDYANINGTYAS, FARIZA NOOR LAILY (2011) FORMULASI TABLET HISAP EKSTRAK PEGAGAN (Centella asiatica L.) DENGAN BASIS MANITOL (Pengaruh Kadar Pengikat PVP K-30 Terhadap Mutu Fisik Tablet). Other thesis, University of Muhammadiyah Malang.

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Abstract

The purpose of this study was determining the effect of PVP K-30 concentration as tablet binder on physical performance of pegagan extract lozenges. The lozenges were prepared by wet granulation method with difference concentration of PVP K-30 (1%, 2%, and 3%). The granules were compressed with hydraulic press at 1 ton pressure. Physically quality test of pegagan extract lozenges had been evaluated, including hardness, friability, and dissolving time. The result show that hardness of pegagan extract lozenges were enhanced by increasing PVP K-30 concentration and the friability was reduced by increasing PVP K-30 concentration, but the dissolving time not enhanced by increasing PVP K-30 concentration. From this observation, it could be concluded that mannitol based pegagan extract lozenges with 2 % concentration of PVP K-30 was the optimum formula.

Item Type: Thesis (Other)
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Health Science > Department of Pharmacy (48201)
Depositing User: Mr Moch. sholeh
Date Deposited: 01 Jun 2016 07:48
Last Modified: 01 Jun 2016 07:48
URI : http://eprints.umm.ac.id/id/eprint/31262

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