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PENGARUH BAHAN PENGIKAT PVP K-30 TERHADAP MUTU FISIK TABLET EFFERVESCENT EKSTRAK TEH HIJAU (Camellia sinensis L.)

M, FIRMAN (2014) PENGARUH BAHAN PENGIKAT PVP K-30 TERHADAP MUTU FISIK TABLET EFFERVESCENT EKSTRAK TEH HIJAU (Camellia sinensis L.). Other thesis, University of Muhammadiyah Malang.

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Abstract

Antioxidants are widely used in Indonesian is butyl hidroksianisol ( BHA ) , butyl hydroxy toluene ( BHT ) and tert - butyl hidoksi quinones ( TBHQ ) , all of which are antioxidants synthesized from chemicals, but the use of large quantities and can be done continuously side effects on human health . Natural antioxidant plant compounds generally are phenolic or polyphenolic compounds that can form the flavonoids , sinamat acid derivatives , coumarin , tocopherol and acid - an organic acid polifungsional . The flavonoids that have antioxidant activity includes flavones , flavonols , isoflavones , catechins , flavanols and chalcon , and nutritious crops as antioxidants is tea ( Camellia sinensis L. ) . The purpose of this study was to determine the effect of 1% , 2 % , and 3 % in the binder PVP K -30 in effervescent tablets formulation of green tea extract ( Camellia sinensis L. ) on tablet physical quality requirements . Manufacture of effervescent tablets with PVP K -30 1 % , 2 % , and 3 % is done by wet granulation method . Results of statistical analysis one- way ANOVA with SPSS confidence level of 95 % , followed by Tukey HSD to indicate a significant difference in the physical quality of each tablet formulation to increase the rate of binder PVP K -30 . So it can be concluded with an increased rate of PVP K -30 fasteners to increase hardness , reduce vulnerability and increase the time dissolves , however, does not always give a meaningful difference to hardness , fragility and time of each formulatoin dissolves. . Key words: Quality Physical, Effervescent Tablets, Green Tea Extract, PVP K-30

Item Type: Thesis (Other)
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Health Science > Department of Pharmacy (48201)
Depositing User: Mr Moch. sholeh
Date Deposited: 02 May 2016 10:26
Last Modified: 02 May 2016 10:26
URI : http://eprints.umm.ac.id/id/eprint/28924

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