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STUDI PENGGUNAAN OBAT GOLONGAN ACE-INHIBITOR PADA PASIEN STROKE ISKEMIK (Penelitian Di Rumah Sakit Umum Dr. Saiful Anwar Malang)

SUTRIANI, . (2013) STUDI PENGGUNAAN OBAT GOLONGAN ACE-INHIBITOR PADA PASIEN STROKE ISKEMIK (Penelitian Di Rumah Sakit Umum Dr. Saiful Anwar Malang). Other thesis, University of Muhammadiyah Malang.

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Abstract

Background: Stroke is a syndrome consisting of rapidly developing (usually seconds or minutes) symptoms and/or signs of loss of focal (or sometimes global) CNS function. The symptoms last more than 24 hours or lead to death. Hypertension is a major risk factor for the incidence of cerebral infarction and intracranial hemorrhage. One of the antihypertensive drugs that used in patients with ischemic stroke is ACE-inhibitors, based on several studies revealed that ACE-inhibitors have significant effectiveness to decrease the mortality rate of patients with myocardial infarction and stroke. Objectives: The study aims to determine patterns of ACE-Inhibitor utilization at patients with ischemic stroke and to examine the relationship of ACE-inhibitor therapy related to the type, dose, route, frequency, interval, and duration of use was associated with clinical data and laboratory data of ischemic stroke patients . Methods: The study is a retrospective observational with consecutive sampling method in ischemic stroke patients from october to december 2012. Result & Conclusion: This study showed there were 14 patients (30.4%) received single of ACE-inhibitor, with the type, dosage, frequency and route dominated by captopril (3x25mg) orally, 10 patiens (71,6%). The use of ACE-inhibitors with combination of other antihypertensive were 32 patients (69.6%), with the combination, dominated by captopril (3x25mg) and amlodipine (1x10 mg) orally, 10 patients (31.3% ). The use of ACE-inhibitors are given in ischemic stroke patients hospitalized at Dr. Saiful Anwar Malang hospitals, are in accordance with the guidelines.

Item Type: Thesis (Other)
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Health Science > Department of Pharmacy
Depositing User: Mr Moch. sholeh
Date Deposited: 22 Apr 2016 09:40
Last Modified: 22 Apr 2016 09:40
URI : http://eprints.umm.ac.id/id/eprint/27791

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